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The Comprehensive Neurotransmitter Profile test is a non-invasive urinary assessment of the body's ability to secrete and metabolise neurotransmitters.


Neurotransmitters are secreted all through the body, in neurons of both the central and peripheral nervous systems. The enzymes, cofactors and precursors in neurotransmitter metabolism are similar in the periphery and in the central nervous system so alterations in urinary neurotransmitter levels provide clinically important information and valuable insights for a range of health concerns.


Neurotransmitter analysis provides an overall assessment of a patient's ability to synthesize and metabolize neurotransmitters, which must occur in both the peripheral nervous system and behind the blood brain barrier (BBB). Alterations in urinary neurotransmitter status may result from a variety of conditions including metabolic disorders, mood/behavioural disorders, environmental exposures or (rarely) the presence of certain tumours. Evaluation of neurotransmitters may provide increased clarity about a patient's health and functional status.


Use This Test If You Suffer With:

  • Mood concerns, such as depression and anxiety
  • Diminished energy/fatigue
  • Insomnia
  • Cognitive concerns such as forgetfulness, inattention or brain fog
  • Addiction and dependency
  • Obsessions and cravings
  • Chronic illness
  • Immune deficiency
  • Pain
  • Low libido and sexual dysfunction
  • Adrenal dysfunction
  • Hormonal Imbalances: E2 dominance, E2 deficiency, low androgens
  • Loss of appetite control: obesity and insulin resistance



  • 3
  • 3-Methoxytyramine (3-MT)
  • 5-Hydroxyindolacetate (5HIAA)
  • Acetate
  • Butyrate
  • Creatinine
  • Dopamine
  • Epinephrine
  • Gamma-aminobutyrate (GABA)
  • Glutamate
  • Glycine
  • Histamine
  • Metanephrine
  • Norepinephrine
  • Norepinephrine / Epinephrine ratio
  • Normetanephrine
  • Phenethylamine (PEA)
  • Serotonin
  • Taurine
  • Tryptamine
  • Tyramine
  • Tyrosine

Comprehensive Neurotransmitter Profile Test

  • All ordered tests will be mediated by our Naturopath, Lekita Davies. Once test results have been returned to us, Lekita will call the client to deliver the results and discuss anything appropriate for the case. After the phone call, results will be emailed to the client alongside any suggestions. Please note that we cannot deliver results without a phone call.

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